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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP35 All Species: 24.24
Human Site: S279 Identified Species: 41.03
UniProt: Q8NFH5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFH5 NP_612142.2 326 34774 S279 G T P T Q P G S T P R I S T M
Chimpanzee Pan troglodytes XP_001160265 337 36129 S290 G T P T Q P G S T P R I S T M
Rhesus Macaque Macaca mulatta XP_001102848 326 34769 S279 G T P T Q P G S T P R I S T M
Dog Lupus familis XP_535992 406 43346 S359 G T P T Q P G S T P R I S T M
Cat Felis silvestris
Mouse Mus musculus Q8R4R6 325 34767 S278 G T P T Q S G S T P R V S T M
Rat Rattus norvegicus Q68FY1 325 34783 S278 G T P T Q P G S T P R V S T M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516155 235 24557 L189 F A Q Y G N I L K H V M S N T
Chicken Gallus gallus XP_421854 325 34473 N278 G T P V Q P A N T T K I S T M
Frog Xenopus laevis NP_001085157 318 33973 G270 G T P T Q S A G T P R A A S M
Zebra Danio Brachydanio rerio Q6P6X9 308 32866 L261 P C T P S H P L S T P R S V M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573314 331 35081 P283 P N A E I G D P P T S P S A I
Honey Bee Apis mellifera XP_396287 584 64120 T537 P E Y S T P R T P I R I Q S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200424 554 60750 N297 A K R L V S Q N A E P E A V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03790 475 52600 L356 A L K Q L A S L K K S E E I I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 99.6 78 N.A. 92.9 94.4 N.A. 63.1 83.4 73.3 71.4 N.A. 27.1 22.6 N.A. 24.3
Protein Similarity: 100 95.8 100 79.3 N.A. 96 97.2 N.A. 65.9 91.4 84 82.2 N.A. 45 32.5 N.A. 36.4
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 6.6 66.6 60 13.3 N.A. 6.6 20 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 13.3 80 73.3 20 N.A. 13.3 40 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 8 0 0 8 15 0 8 0 0 8 15 8 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 8 0 0 0 0 0 8 0 15 8 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 58 0 0 0 8 8 43 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 8 0 0 8 0 43 0 8 15 % I
% Lys: 0 8 8 0 0 0 0 0 15 8 8 0 0 0 0 % K
% Leu: 0 8 0 8 8 0 0 22 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 65 % M
% Asn: 0 8 0 0 0 8 0 15 0 0 0 0 0 8 0 % N
% Pro: 22 0 58 8 0 50 8 8 15 50 15 8 0 0 0 % P
% Gln: 0 0 8 8 58 0 8 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 8 0 0 0 8 0 0 0 58 8 0 0 8 % R
% Ser: 0 0 0 8 8 22 8 43 8 0 15 0 72 15 0 % S
% Thr: 0 58 8 50 8 0 0 8 58 22 0 0 0 50 8 % T
% Val: 0 0 0 8 8 0 0 0 0 0 8 15 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _